

I would personally use Debian as my first choice then use Ubuntu if there is a reason to use it over Debian. For example Ubuntu will often integrate drivers for new devices faster than Debian. But if you are dealing with hardware released more 1 year ago, I wouldn’t worry about that. Also, some applications will specifically call out Ubuntu as their supported distro.
I run Truenas scale on home server and on the off-site backup at a friend’s house. ZFS Snapshots get synced to backup server nightly. The snapshot system is nice because it only needs to send what has changed since the last synced snapshot.
Now that I have it setup it is mostly no effort on my part. But the initial ramp up to understand Truenas and ZFS was a second job for a few weeks. HexOS may be good choice if you want the power of Truenas but the handholding of setup wizards and such. But HexOS is currently $200 and Truenas is free. Pay in time or dollars.