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Proxmox (debian) on the hosts, and Debian for all the VMs and Containers.
Just nice and easy to use, supported by basically everything, and a minimal install uses like 30MB of RAM.
I also have an OSX VM because that’s literally the only way you can test a website in Safari (fu Apple).
Love proxmox. Been using it for nearly a decade and while it has its pain points it has been rock solid for me for the past 4 years.
You don’t need Safari unless it’s for Apple Pay integration or something. WebKit is open source. Use Epiphany or some other browser that uses it.