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That depends on your use case for desktop linux of course. For me, yabridge is the tool I needed to run VSTs on Linux. Its CLI only as far as I know.
Don’t get me wrong; I’m not afraid of the CLI. Its just some tools are assuming the end user is a server admin or someone with deeper than the upper crust knowledge of how Linux works.
yabridge
Ah, that’s a pretty niche use-case. But yeah, the deeper you go, the more you’ll have to rely on the CLI.